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Table 3 Nucleotide mutation and amino acid substitution in HPV-33 E6

From: The polymorphism analysis and epitope predicted of Alphapapillomavirus 9 E6 in Sichuan, China

 

HPV-33 E6

No

1

2

3

4

5

6

7

8

Location

105

165

221

256

279

338

434

441

Mutation

A–C

A–G

G–C

A–C

A–C

A–G

G–T

T–C

Frequency (%)

19.44

7.87

3.24

7.41

19.44

7.41

15.28

11.57

Substitution

K35N

–

S74T

N86H

K93N

Q113R

R145I

–

  1. Compared with the HPV-33 E6 reference sequence (M12732.1), the mutations are marked with the corresponding bases and amino acid, and those without changes are replaced with a dash (–). No. means the number of nucleotide mutations, Location means the sites of nucleotide mutations, Mutation means the style of nucleotide mutations, Frequency (%) means the percentage of nucleotide mutations, Substitution means the amino acid substitution that occurred by nucleotide mutations