Fig. 1
From: Analysis of the intestinal microbial community altered during rotavirus infection in suckling mice
Changes in suckling mice infected with rotavirus strain SA-11. a The viral load in the feces of the suckling mice in the RV group was quantified by a fluorescent focus assay (FFA) with MA104 cells. No virus was detected in NC group. The RV group contained 10 litters of mice, and there were 7–8 mice in each litter. Each experiment was repeated three times. b Histopathological changes within the duodenum of mice challenged with RV-SA11 as demonstrated by H&E staining. Five sucking mice were randomly selected from each RV group and NC group for sample collection and pathological analysis. a: vacuolar degeneration of intestinal epithelial cells; b: congestion and edema of the stroma, dilation, and congestion of blood vessels distributed within the villi of the small intestine; c: necrosis of cells; and d: destruction of the intestinal epithelium. Scale bar = 50 μm (a); 20 μm (b, c, and d)