Fig. 1From: IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3ZIKV replicates and IRF2 is induced in A549 cells. A549 cells were infected with ZIKV (MOI = 0.5) or left uninfected and total cellular RNAs were extracted at different hours-post-infection (hpi). RNA levels of ZIKV NS5 (a), IRF2 (b), ISG15 (c) and IFIT1 (d) were measured by RT-qPCR. Protein levels of ZIKV-NS1 and IRF2 were measured by western blots (d). Data were presented as mean ± standard deviation (SD) representative of at least three independent experimentsBack to article page