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Fig. 5 | Virology Journal

Fig. 5

From: Nanoparticles of conformation-stabilized canine distemper virus hemagglutinin are highly immunogenic and induce robust immunity

Fig. 5

ELISpot analysis of CDV H-specific IFN-γ and IL-4 secretion. The spleen and lymph node were collected from each group 2 weeks after the final immunization. Lymphocytes from the spleen and lymph node were stimulated with soluble CDV H protein, tH, and flagellin. The IFN-γ and IL-4 cytokine-secreting cells were determined using ELISpot assay. The secretion of IFN-γ and IL-4 in the spleen (a) and lymph node (b). * P < 0.05, **P < 0.01

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Virology Journal

ISSN: 1743-422X