Serotype-dependent recombinant adeno-associated vector (AAV) infection of Epstein–Barr virus-positive B-cells, towards recombinant AAV-based therapy of focal EBV + lymphoproliferative disorders

Table 1 rAAV EGFP Serotypes

Fifteen distinct serotypes of rAAV, including four serotypes derived from rhesus monkeys (rh) were obtained according to procedures developed in the Horae Gene Therapy Center at the University of Massachusetts Medical School (Methods). Virions were produced in HEK293 cells (Methods). Virus titer was expressed as genome copies per ml (GC/ml). Titers were subsequently normalized for comparative transduction assays

ISSN: 1743-422X