Fig. 2

SARS-CoV-2 variants in Paraná state identified by genome sequencing. a Frequency and temporal distribution of the SARS-CoV-2 variant from February 2020 to April 2021. Information on the number of sequenced genomes and identification of variants from February 2020 to February 2021 were retrieved from the website genomahcov.fiocruz.br. The”Genomes” line indicates the number of representative sequences that were used to estimate the variant frequency at each time point. b Phylogenetic analysis of SARS-CoV-2 genomes identified in the state of Paraná. High-quality genomic sequences (n < 5%) were aligned using Mafft software in the default configuration. The phylogenetic tree was built using the maximum likelihood method in IQTree software and visualized in IToL. The scale of the phylogenetic branches is given as substitutions per nucleotide site. Each symbol represents a SARS-CoV-2 lineage, as shown in the legend. The lineage N.10 is highlighted in red; the lineage P.2 is highlighted in light yellow; the Gamma-like-II genomes are highlighted in light green; Gamma sequences harboring S:E661D are highlighted in shadow golden and Wuhan-Hu-1 is highlighted in orange