Fig. 4

GO enrichment highlights include biological process, cell composition, molecular function, and the KEGG signaling pathway enrichment bubble graphic, from top to bottom. The size of − Log₁₀(P.Value) in the GO enrichment map is indicated by the blue bar, and the number of genes enriched in each GO annotation is indicated by the yellow line. In the KEGG signal pathway enrichment bubble diagram, the size of the bubble reflects the number of genes enriched in each signal pathway, and the color of the spots reflects its significance level