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Table 2 Current knowledge on recent parvoviruses of veterinary importance based on Koch’s revisited postulates

From: Small but mighty: old and new parvoviruses of veterinary significance

 

I: genome sequence in most cases of infectious disease

II: fewer/no genome copies in hosts/tissue without disease

III: copy number decreases with disease resolution

IV: sequence detection prior to disease or copy number correlates with severity

V: virus phenotype is consistent with known biological characteristics of its group

VI: in situ hybridization detection of genome copies in tissues with pathology

VII: genome sequence-based evidence is experimentally reproducible

Total number of criteria addressed

Skunk amdoparvo-virus (SKAV)

 + [72,73,74, 78, 79]

 + [72,73,74, 78, 79]

NA

NA

 + 

 + [73, 78]

NA

4

Red panda amdoparvo-virus (RpAPV)

NA

NA

NA

NA

 + 

 + [10]

NA

2

Feline bocaviruses (FBoV1-3)

NA

NA

NA

NA

 + 

 + [131]

NA

2

Canine bocavirus 2 (CBoV2)

 + [133,134,135]

 + [133,134,135]

NA

NA

 + 

 + [135]

NA

4

Equine parvovirus-hepatitis (EqPV-H)

 + [4, 5, 153, 154]

 + [4]

 + [4]

 + [4]

 + [4, 5]

 + [3, 4]

6

Seal parvovirus (SePV)

NA

NA

NA

NA

 + [218]

NA

1

Porcine parvovirus 2 (PPV2)

NA

[281, 283, 285]

NA

NA

 + 

 + [286]

NA

2

Mouse kidney parvovirus (MKPV)

 + [7, 8, 11]

 + [7, 8, 11]

NA

 + [7, 8, 11]

 + 

 + [7, 8, 11]

 + [7, 8, 11]

6

Tilapia parvovirus (TiPV)

 + [6]

 + [6]

NA

 + [6]

 + 

 + [6]

 + [6]

6

  1. The seven revisited criteria, adapted from Fredericks and Relman [13], are shown. Evaluation of evidence for pathogenicity was based on total number of criteria addressed for each virus and classified as weak (score 1–2), moderate (score 3–5), or strong (score 6–7)
  2. NA not assessed yet/not feasible/not applicable