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Table 6 Detection of hrHPV mRNA categorized by age group

From: High-risk human papillomavirus detection in self-collected vaginal samples compared with healthcare worker collected cervical samples among women attending gynecology clinics at a tertiary hospital in Pretoria, South Africa

Age category (in years) Participants per age group Healthcare worker-sampling Self-sampling P-value*
hrHPV mRNA Positive (%) hrHPV mRNA Negative (%) hrHPV mRNA Positive (%) hrHPV mRNA Negative (%)
≤ 29 99 64 (64.6) 35 (35.4) 53 (53.5) 46 (46.5) 0.0614
30–39 84 70 (83.3) 14 (16.7) 52 (61.9) 32 (38.1) 0.0001
40–49 67 61 (91.0) 6 (9.0) 41 (61.2) 26 (38.8) < 0.0001
50–59 28 23 (82.1) 5 (17.9) 16 (57.1) 12 (42.9) 0.0654
≥ 60 7 6 (85.7) 1 (14.3) 5 (71.4) 2 (28.6) 1.0000
Total 285 224 (78.6) 61 (21.4) 167 (58.6) 118 (41.4) < 0.0001
  1. *McNemar test for correlated proportions