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Fig. 2 | Virology Journal

Fig. 2

From: Mechanism of interaction between virus and host is inferred from the changes of gene expression in macrophages infected with African swine fever virus CN/GS/2018 strain

Fig. 2

Changes in differential gene expression in PAM at different times after ASFV infection. A RT-qPCR vs. RNA-seq analyses of the expression for representative six genes (IL33, IFITM3, BMP8A, CDKN2B, HPSE, and MARCO). B The principal component analysis (PCA). C The upregulated/downregulated and the total number of DEGs (≥ 2 FC, P < 0.05) at 12, 24, and 36 h after PAMs infected by ASFV (MOI = 1). D Venn diagrams show an overlap of ASFV-induced DEGs across 12, 24, and 36 hpi. The fold-difference was measured by the 2−ΔΔCt method. The RNA levels were normalized to corresponding GAPDH. Data are presented as mean ± SD of three independent experiments

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Virology Journal

ISSN: 1743-422X