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Table 1 PUUV infection and release of human primary pulmonary cells

From: Cells of the human respiratory tract support the replication of pathogenic Old World orthohantavirus Puumala

Cell type

% infected cells (mean ± SD)

Infectious units/ml (mean ± SD)

2 dpi

4 dpi

6 dpi

SN 2 dpi

SN 4 dpi

SN 6 dpi

HPMEC #011

34.6 ± 9.8

63.9 ± 5.9

82.8 ± 3.6

1.7 × 105 ± 3.8 × 104

6.3 × 104 ± 1.8 × 103

1.0 × 104 ± 2.2 × 103

HPMEC #016

18.5 ± 1.8

33.0 ± 2.9

53.7 ± 2.7

0.4 × 104 ± 0.1 × 104

1.0 × 104 ± 0.2 × 104

2.4 × 104 ± 0.4 × 104

HBEpC #359

18.3 ± 3.1

12.2 ± 1.1

60.4 ± 4.2

8.8 × 104 ± 8.0 × 103

2.8 × 105 ± 2.1 × 104

1.9 × 105 ± 2.1 × 104

HBEpC #404

13.7 ± 3.8

16.0 ± 1.6

29.0 ± 2.1

4.8 × 102 ± 4.1 × 102

4.2 × 103 ± 2.1 × 103

8.9 × 103 ± 2.7 × 103

HSAEpC #210

9.6 ± 1.9

24.1 ± 1.1

27.4 ± 5.9

3.2 × 104 ± 1.8 × 104

4.2 × 105 ± 8.2 × 104

4.2 × 104 ± 5.9 × 103

HSAEpC #306

47.1 ± 2.8

66.8 ± 0.3

85.2 ± 0.4

6.1 × 104 ± 1.4 × 104

2.3 × 105 ± 2.2 × 104

5.4 × 104 ± 1.6 × 103

HPAEpiC #144

16.2 ± 3.2

51.7 ± 5.5

45.4 ± 1.3

1.5 × 103 ± 1.2 × 102

8.8 × 103 ± 6.7 × 102

3.8 × 103 ± 1.4 × 103

HPAEpiC #167

9.3 ± 1.8

90.3 ± 1.6

77.5 ± 0.4

9.1 × 103 ± 5.9 × 103

5.3 × 103 ± 4.0 × 102

7.3 × 103 ± 3.7 × 103

  1. SD standard deviation, SN supernatant, dpi days post infection