Fig. 1
From: Apoptotic investigation of brain tissue cells in dogs naturally infected by canine distemper virus
Severe CDV-infected endothelia and astrocytes A CDV antigen intense positive reaction in the endothelium (up arrow) of the blood vessel. sABC staining, Bar = 20 μm. B CDV antigen intense positive reaction of endothelia (up arrow) and astrocytic food processes (up arrow) surrounding the blood vessels and astrocytes. sABC staining, Bar = 20 μm. C Astrocytes located in mild and moderate demyelinating areas are intense positive reactions (up arrow) against GFAP. Anti-GFAP staining, Bar = 50 μm. D Apoptosis of endothelia (up arrow) and star-patterned astrocytes (up arrow) are detected in primary demyelinating areas. TUNEL staining, Bar = 50 μm