Skip to main content

Table 2 Antiviral Activity of crude aqueous fraction and partially purified peptide fractions on three NPESC members

From: In vitro antiviral activity of peptide-rich extracts from seven Nigerian plants against three non-polio enterovirus species C serotypes

Extract CC50 (µg/mL) CV-A13 CV-A20 EV-C99
IC50 (µg/mL) SI IC50 (µg/mL) SI IC50 (µg/mL) SI
ABp 167.2 33.31 5.0 NA NA NA NA
ACc 24.3 NA NA 2.67 9.1 1.64 14.8
ACp 20.5 NA NA 1.09 18.8 1.18 17.3
ICc 109.8 NA NA 1.75 62.9 1.85 59.5
ICp 19.7 NA NA 0.54 36.4 0.54 36.8
EHic 81.6 2.81 29.0 1.65 49.3 0.80 102.5
EHip 159.0 0.94 169.0 1.96 81.0 0.53 301.7
EHuc 167.5 17.28 9.7 19.57 8.6 9.45 17.7
EHup 169.0 20.94 8.1 5.47 30.9 5.30 31.9
EGc 33.2 1.969 16.8 NA NA 0.644 51.6
EGp 39.1 3.203 12.2 1.663 23.5 0.531 73.6
PAp 68.0 NA NA 1.11 61.5 0.59 116.3
  1. c—crude aqueous fraction; p—partially purified peptide fraction; NA—not active; SI—selective index; CC50—50% cytotoxic concentration; IC50—50% inhibitory concentration; CVA13—Coxsackievirus A13; CVA20—Coxsackievirus A20; EVC99—Enterovirus C99