Table 4 SVR12 of LDV/SOF by regimen and different treatment duration
Response | SVR12 (N = 711) | Heterogeneity | Pb value | Studies | ||
|---|---|---|---|---|---|---|
Total, n/N | Rate (95% CI) | I2 (%) | Pa | |||
Overall | 644/711 | 89.8 (85.9–92.7) | 47.6 | 0.0336 |  | 12 |
By regimes | ||||||
 LDV/SOF | 436/484 | 89.2 (83.4–93.1) | 55.6 | 0.7452 | 0.0274 | 9 |
 LDV/SOF ± RBV | 193/211 | 90.4 (83.6–94.5) | 28.9 |  |  | 5 |
By different treatment duration | ||||||
 8 | 93/101 | 88.0 (70.7–95.7) | 46.2 | 0.8774 | 0.2627 | 5 |
 12 | 74/82 | 89.9 (81.0–94.9) | 0.0 |  |  | 3 |
 24 | 16/18 | 82.2 (24.9–98.5) | 58.2 |  |  | 2 |