Number of pregnancy cases
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n = 17 (17 out of 1,106; 1.54%)
|
Age (years)
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32 (range 17–41)
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Gravidity
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G1: n = 9 (52.9%), G2: n = 5 (29.4%), G3: n = 3 (17.6%)
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Twin/Triplet pregnancy
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n = 3 (17.6%)
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Gestational age
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First trimester: n = 1 (5.9%), Second trimester: n = 2 (11.8%), Third trimester: n = 14 (82.4%)
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Clinical/laboratory presentations
| |
Hyperbilirubinemia
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n = 8 (47.1%)
|
Elevation of AST or ALT > 100 U/L
|
n = 13 (76.5%)
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Liver function test (All 17 cases)
| |
AST (U/L)
|
143 (24–1,576)
|
ALT (U/L)
|
242 (19–1,708)
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ALP (U/L)
|
196 (57–500)
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TB (mg/dL)
|
2.04 (0.3–24.3)
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Diagnoses
| |
Recent viral hepatitis
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n = 4 (23.5%); HAV (n = 1), HBV (n = 2), HEV (n = 2)
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Acute fatty liver in pregnancy
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n = 5 (29.4%); one was also diagnosed with syphilis
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Pre-eclampsia/HELLP
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n = 3 (17.6%)
|
Others
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ATV/r induced hyperbilirubinemia (n = 1), chronic HT with UGIB (n = 1), acute/post-arrest hepatitis (n = 2), pregnancy with DFIU (n = 1)
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Pregnancy and fetal complications
| |
Ectopic pregnancy/DFIU
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n = 2 (11.8%)
|
Threaten preterm labor/preterm labor
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n = 3 (17.6%); from maternal HAV infection (n = 1), maternal HBV infection (n = 1)
|
Low infant birth weight (< 2,500 g)
|
n = 10 (58.9%); from maternal HAV infection (n = 1), maternal HBV infection (n = 1), maternal HEV infection (n = 1)
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Timing of anti-HEV antibody test
|
Pre-partum: n = 7 (41.2%), Peri/Post-partum: n = 10 (58.9%)
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Results of anti-HEV antibody test
| |
Positive anti-HEV IgG antibody
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n = 7 (41.2%); two cases were also tested positive for anti-HEV IgM
|
Positive anti-HEV IgM antibody
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n = 2 (11.8%)
|