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Table 1 The prevalence of human herpesvirus 8 (HHV-8) in uterine cervical samples, stratified by several factors

From: The prevalence of human herpesvirus 8 in normal, premalignant, and malignant cervical samples of Iranian women

Total

HHV-8 status

p-value

Positive N (%)

Negative N (%)

Total N (%)

62 (17)

302 (83)

364 (100)

Samples

Normal

26 (14.5)

153 (85.5)

179 (100)

 

Premalignant

22 (17.7)

102 (82.3)

124 (100)

0.308

Malignant

14 (22.9)

47 (77.1)

61 (100)

 

Total

62 (17.0)

302 (83.0)

364 (100)

 

Sample types

FFPE

18 (15.8)

96 (84.2)

114 (100)

 

Thin-prep

44 (17.6)

206 (82.4)

250 (100)

0.78

Total

62 (17)

302 (83)

364 (100)

 

HPV infection

Positive

59 (20.3)

233 (79.7)

292 (100)

 

Negative

3 (4.0)

69 (96.0)

72 (100)

0.002

Total

62 (17)

302 (83)

364 (100)

 

HPV genotypes

HPV 16/18

19 (15.7)

102 (84.3)

121 (100)

 

High-risk HPVs (non-16/18)

40 (23.4)

131 (76.6)

171 (100)

0.1

Total

59 (20.3)

233 (79.7)

292 (100)

 

Cancer types

SCC

12 (24.0)

38 (76.0%)

50 (100)

 

AC

2 (18.2)

9 (81.8)

11 (100)

0.98

Total

14 (22.9)

47 (77.1)

61 (100)

 

Age group

20–30

7 (11.1)

52 (88.1)

59 (100)

 

30–40

8 (10.8)

66 (89.2)

74 (100)

 

40–50

5 (10.7)

42 (89.3)

47 (100)

0.55

> 50

10 (18.5)

44 (81.5)

54 (100)

 

Total

30 (12.8)

204 (87.2)

234 (100)

 
  1. P-values less than 0.05 are indicated in bold font
  2. SCC: Squamous cell carcinoma and AD: Adenocarcinoma; FFPE: Formalin-fixed paraffin-embedded tissue