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Table 1 The prevalence of human herpesvirus 8 (HHV-8) in uterine cervical samples, stratified by several factors

From: The prevalence of human herpesvirus 8 in normal, premalignant, and malignant cervical samples of Iranian women

Total HHV-8 status p-value
Positive N (%) Negative N (%) Total N (%)
62 (17) 302 (83) 364 (100)
Samples
Normal 26 (14.5) 153 (85.5) 179 (100)  
Premalignant 22 (17.7) 102 (82.3) 124 (100) 0.308
Malignant 14 (22.9) 47 (77.1) 61 (100)  
Total 62 (17.0) 302 (83.0) 364 (100)  
Sample types
FFPE 18 (15.8) 96 (84.2) 114 (100)  
Thin-prep 44 (17.6) 206 (82.4) 250 (100) 0.78
Total 62 (17) 302 (83) 364 (100)  
HPV infection
Positive 59 (20.3) 233 (79.7) 292 (100)  
Negative 3 (4.0) 69 (96.0) 72 (100) 0.002
Total 62 (17) 302 (83) 364 (100)  
HPV genotypes
HPV 16/18 19 (15.7) 102 (84.3) 121 (100)  
High-risk HPVs (non-16/18) 40 (23.4) 131 (76.6) 171 (100) 0.1
Total 59 (20.3) 233 (79.7) 292 (100)  
Cancer types
SCC 12 (24.0) 38 (76.0%) 50 (100)  
AC 2 (18.2) 9 (81.8) 11 (100) 0.98
Total 14 (22.9) 47 (77.1) 61 (100)  
Age group
20–30 7 (11.1) 52 (88.1) 59 (100)  
30–40 8 (10.8) 66 (89.2) 74 (100)  
40–50 5 (10.7) 42 (89.3) 47 (100) 0.55
> 50 10 (18.5) 44 (81.5) 54 (100)  
Total 30 (12.8) 204 (87.2) 234 (100)  
  1. P-values less than 0.05 are indicated in bold font
  2. SCC: Squamous cell carcinoma and AD: Adenocarcinoma; FFPE: Formalin-fixed paraffin-embedded tissue