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Fig. 5 | Virology Journal

Fig. 5

From: Zoonotic vaccinia virus strains belonging to different genetic clades exhibit immunomodulation abilities that are proportional to their virulence

Fig. 5

Immunologic populations from spleen of BALB/c mice uninfected or infected with VACV-BR. Groups of mice (n = 7) were inoculated with PBS or 106 PFU of PSTV, GP1V or VACV-WR by the intranasal route. The percentage of T lymphocytes CD3 + (A), CD4 + (B) and CD8 + (C), monocytes CD14 + (D) and NK cells CD3-CD49 + (E) was determined 7 days post infection by flow cytometry and analyzed using FlowJo software, parameters granularity (SSC) versus size (FSC). The error bars indicate the standard deviations. During the experiment some animals were lost. CETEA does not allow us to increase the number of animals to compensate for this loss. Significance variations were calculated using the One-way ANOVA post hoc Bonferroni with statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Virology Journal

ISSN: 1743-422X