From: Liver injury in COVID-19: clinical features and treatment management
Classification | Definition |
---|---|
Liver injury [3] | ALT and/or AST over 3 × ULN, ALP, GGT, and/or TBIL over 2 × ULN |
Hepatocellular [3] | elevated ALT and/or AST more than 3 × ULN |
Cholestatic [3] | elevated ALP or GGT over twice the ULN |
Mixed (Abnormality) [3] | Both elevated ALT and/or AST more than 3 × ULN, and elevated ALP or GGT over twice the ULN |
Cytokine Storm | The inflammatory markers C-reactive protein (CRP), serum ferritin, LDH, D-dimer, IL-6 and IL-2 in severe COVID-19 patients are significantly increased |
Mild cases of COVID-19 [4] | patient can present as common symptoms: fever, dry cough, fatigue, headache, sore throat |
Severe cases of COVID-19 [4] | Patient who fits any one of the following condition: 1. Respiratory rate ≥ 30 breath/min 2. SpO2 ≤ 93% 3.PaO2/FiO2 ≤ 300 mmHg (1 mmHg = 0.133 kPa) |