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Table 1 The definition of some concepts in this paper

From: Liver injury in COVID-19: clinical features and treatment management

Classification

Definition

Liver injury [3]

ALT and/or AST over 3 × ULN, ALP, GGT, and/or TBIL over 2 × ULN

Hepatocellular [3]

elevated ALT and/or AST more than 3 × ULN

Cholestatic [3]

elevated ALP or GGT over twice the ULN

Mixed (Abnormality) [3]

Both elevated ALT and/or AST more than 3 × ULN, and elevated ALP or GGT over twice the ULN

Cytokine Storm

The inflammatory markers C-reactive protein (CRP), serum ferritin, LDH, D-dimer, IL-6 and IL-2 in severe COVID-19 patients are significantly increased

Mild cases of COVID-19 [4]

patient can present as common symptoms: fever, dry cough, fatigue, headache, sore throat

Severe cases of COVID-19 [4]

Patient who fits any one of the following condition:

1. Respiratory rate ≥ 30 breath/min

2. SpO2 ≤ 93%

3.PaO2/FiO2 ≤ 300 mmHg (1 mmHg = 0.133 kPa)