Fig. 5
From: Inhibition of herpes simplex virus-1 infection by MBZM-N-IBT: in silico and in vitro studies
Inhibition pattern of HSV-1 infection by addition of MBZM-N-IBT at different time points: Vero cells were infected by HSV-1 with MOI 0.001, 2, 5 and 200 µM MBZM-N-IBT was added to different dishes at every 4 h intervals up to 20 hpi. The supernatants, as well as cells were collected from all the experimental samples at 20 hpi and plaque assay was performed to assess the number of infectious particles of HSV-1. The bar diagram represents the virus titer in PFU/mL. Data represent the mean ± SEM from three independent experiments using the one way Anova, Dunnett’s multiple comparisons test. p-value less than 0.001 was considered to be statistically significant in the test