Skip to main content

Table 2 Summarizes the frequencies of comorbidities in terms of median and interquartile range (IQR) recorded for COVID-19 patients by studies included in this review

From: A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?

Comorbidity Frequency (%) Studies reported
Median (%) IQR
Hypertension 28.60 10.8–45.4 8
Cardiovascular diseases 14.60 10.1–21.4 9
Diabetes 13.20 10.2–30.1 12
Cerebrovascular diseases 8.30 2.1–14.3 6
Chronic lung disease 3.20 1.4–15.9 4
Chronic kidney disease 7.20 2.9–20.8 7
Immunocompromised state 4.80 1.1–11.4 6
Chronic liver disease 2.70 1.8–5.0 6
  1. Diabetes was the most frequently recorded comorbidity but hypertension had the highest prevalance amongst patients of the studies that recorded hypertension as a comorbididty. Obesity, underlying endocrine disorders, autoimmune disease, gastrointestinal diseases and obstructive sleep apnea were aslo noted
  2. Chen et al. [73] and Zhang et al. [83] reported presence of cardiovascular and cerebrovascular diseases collectively in 40.4% and 14.3% of their participants respectively
  3. Chen et al. [73] and Zhang et al. [83] also reported presence of underlying chronic gastrointestinal diseases in 11.1% and 9.3%, and underlying endocrine diseases other than diabetes—such as thyroid disorders—in 1.1% and 3.6% of the patients respectively
  4. Richardson et al. [107] and Goyal et al. [108] also reported obesity in 60.6% and 35.8% of their participants
  5. Chen et al. also recorded presence of autoimmune disease in 1.1% of their participants [73]
  6. Obstructive Sleep Apnea (OSA) was noted by Richardson [106], Arentz [109], and Bhatraju [66] as comorbidity amongst 2.7%, 28.8% and 20.8% of their participants respectively