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Table 3 Univariate analysis of the patients who reached the composite end point and the patients who failed to reach the composite end point

From: Intravenous immunoglobulin-based adjuvant therapy for severe COVID-19: a single-center retrospective cohort study

Parameter

Patients who reached the composite end point

n = 96

Patients who failed to reach the composite end point

n = 17

P

Age

54.0 (45.2–62.0)

59.0 (52.0–73.5)

0.042

Female

48 (50.0%)

4 (23.5%)

0.044

Comorbidity

28 (29.2%)

11 (64.7%)

0.004

Hypertension

19 (19.8%)

7 (41.2%)

0.053

Diabetes

9 (9.4%)

4 (23.5%)

0.092

Coronary heart disease

4 (4.2%)

3 (17.6%)

0.034

COPD

4 (4.2%)

2 (11.8%)

0.198

Cerebrovascular disease

2 (2.1%)

2 (11.8%)

0.046

Time of onset

7.0 (5.0–10.0)

7.0 (6.5–10.0)

0.499

Body temperature

38.4 (37.6–39.0)

38.9 (38.2–39.4)

0.041

WBC

5.28 (4.02–7.22)

8.43 (6.58–16.21)

0.001

LYM

1.12 (0.78–1.54)

0.67 (0.55–1.03)

0.001

PLT

201.0 (159.2–258.5)

191.0 (124.0–213.5)

0.086

ALT

23.0 (15.0–34.7)

29.7 (21.5–74.0)

0.065

AST

20.6 (17.0–27.0)

36.0 (18.0–45.4)

0.029

Cr

76.6 ± 22.2

88.6 ± 30.5

0.056

PT

11.4 ± 1.2

12.9 ± 1.6

 < 0.001

DD

172.0 (107.9–285.5)

851.0 (217.0–9954.5)

 < 0.001

GC

43 (44.8%)

14 (82.4%)

0.004

IVIG

35 (36.5%)

12 (70.6%)

0.008

  1. IVIG intravenous immunoglobulin, COPD chronic obstructive pulmonary disease, WBC white blood cell, LYM lymphocyte, PLT platelet, ALT alanine aminotransferase, AST aspartate aminotransferase, Cr serum creatinine, PT prothrombin time, DD d-dimer, GC Glucocorticoid