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Table 1 Summary of the chronological order of events from admission to discharge

From: Simultaneous enterovirus EV-D68 and CVA6 infections causing acute respiratory distress syndrome and hand, foot and mouth disease

Date

Event

Initial presentation

Symptoms: fever (38Ā Ā°C), abdominal pain and tachycardia

Days 2ā€“5 post-initial presentation

Erythematous and pruritic lesions arose on the palms and soles of the feet, perioral region and ears, which further evolved to vesicles in hands, feet, mouth, and ears

Days 6ā€“14 post-initial presentation (second admission)

Fever (39Ā Ā°C), cough, respiratory distress (O2 saturation of 85ā€“88%), vesicles and crusts on hands, face, and ears, blood pressure unstable, acute myocarditis

Days 15ā€“16 post-initial presentation

Improvement of systolic function and arterial pressure. The child was discharged from the PICU and maintained in oxygen therapy (O2 saturation of 98%)

Days 20 post-initial presentation

After complete recovery, the patient was discharged