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Table 3 Algorithm to estimate risk for hospital mortality using total points for risk scores with logistic regression analysis in the severe patients with COVID-19 from training dataset

From: Scores based on neutrophil percentage and lactate dehydrogenase with or without oxygen saturation predict hospital mortality risk in severe COVID-19 patients

Variables Categories Reference value (Wij) Bi Regression units Βi (Wij—WiREF) Points assigned Βi (Wij—WiREF)/B
NSL risk score (NE +  SaO2 + LDH)      
 NE (%)    0.127   
   ≤ 60 55 (WiREF)   0.000 0
  60.1–70 65   1.270 4
  70.1–80 75   2.540 8
  80.1–90 85   3.810 12
   ≥ 90.1 95   5.080 16
 SaO2 (%)    -0.175   
  100–96 98 (WiREF)   0.000 0
  95–91 93   0.875 3
  90–86 88   1.750 6
   ≤ 85 83   2.625 9
 LDH (U/L)    0.003   
   ≤ 221 171 (WiREF)   0.000 0
  222–321 271   0.300 1
  322–421 371   0.600 2
  422–521 471   0.900 3
  522–621 571   1.200 4
  622–721 671   1.500 5
  722–821 771   1.800 6
  822–921 871   2.100 7
  922–1021 971   2.400 8
   ≥ 1022 1071   2.700 9
NL risk score (NE + LDH)      
 NE (%)    0.158   
   ≤ 60 55 (WiREF)   0.000 0
  60.1–70 65   1.580 4
  70.1–80 75   3.160 8
  80.1–90 85   4.740 12
   ≥ 90.1 95   6.320 16
 LDH (U/L)    0.004   
   ≤ 221 171 (WiREF)   0 0
  222–321 271   0.400 1
  322–421 371   0.800 2
  422–521 471   1.200 3
  522–621 571   1.600 4
  622–721 671   2.000 5
  722–821 771   2.400 6
  822–921 871   2.800 7
  922–1021 971   3.200 8
   ≥ 1022 1071   3.600 9
  1. Wij, reference value for each category of risk factors in risk score; WiREF, the base category for each risk factor was used as the basic value for that factor and assigned 0 point. Bi, the regression coeffcient of each risk factor from logistic regression; B, the smallest regression units or the smallest units divided by some constant (B = 0.3 for NSL risk score and B = 0.4 for NL risk score)