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Table 3 Algorithm to estimate risk for hospital mortality using total points for risk scores with logistic regression analysis in the severe patients with COVID-19 from training dataset

From: Scores based on neutrophil percentage and lactate dehydrogenase with or without oxygen saturation predict hospital mortality risk in severe COVID-19 patients

Variables

Categories

Reference value (Wij)

Bi

Regression units Βi (Wij—WiREF)

Points assigned Βi (Wij—WiREF)/B

NSL risk score (NE +  SaO2 + LDH)

     

 NE (%)

  

0.127

  
 

 ≤ 60

55 (WiREF)

 

0.000

0

 

60.1–70

65

 

1.270

4

 

70.1–80

75

 

2.540

8

 

80.1–90

85

 

3.810

12

 

 ≥ 90.1

95

 

5.080

16

 SaO2 (%)

  

-0.175

  
 

100–96

98 (WiREF)

 

0.000

0

 

95–91

93

 

0.875

3

 

90–86

88

 

1.750

6

 

 ≤ 85

83

 

2.625

9

 LDH (U/L)

  

0.003

  
 

 ≤ 221

171 (WiREF)

 

0.000

0

 

222–321

271

 

0.300

1

 

322–421

371

 

0.600

2

 

422–521

471

 

0.900

3

 

522–621

571

 

1.200

4

 

622–721

671

 

1.500

5

 

722–821

771

 

1.800

6

 

822–921

871

 

2.100

7

 

922–1021

971

 

2.400

8

 

 ≥ 1022

1071

 

2.700

9

NL risk score (NE + LDH)

     

 NE (%)

  

0.158

  
 

 ≤ 60

55 (WiREF)

 

0.000

0

 

60.1–70

65

 

1.580

4

 

70.1–80

75

 

3.160

8

 

80.1–90

85

 

4.740

12

 

 ≥ 90.1

95

 

6.320

16

 LDH (U/L)

  

0.004

  
 

 ≤ 221

171 (WiREF)

 

0

0

 

222–321

271

 

0.400

1

 

322–421

371

 

0.800

2

 

422–521

471

 

1.200

3

 

522–621

571

 

1.600

4

 

622–721

671

 

2.000

5

 

722–821

771

 

2.400

6

 

822–921

871

 

2.800

7

 

922–1021

971

 

3.200

8

 

 ≥ 1022

1071

 

3.600

9

  1. Wij, reference value for each category of risk factors in risk score; WiREF, the base category for each risk factor was used as the basic value for that factor and assigned 0 point. Bi, the regression coeffcient of each risk factor from logistic regression; B, the smallest regression units or the smallest units divided by some constant (B = 0.3 for NSL risk score and B = 0.4 for NL risk score)