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Fig. 7 | Virology Journal

Fig. 7

From: Intranasal delivery of plasmids expressing bovine herpesvirus 1 gB/gC/gD proteins by polyethyleneimine magnetic beads activates long-term immune responses in mice

Fig. 7

Evaluation of cellular immune responses induced by DNA vaccine in vaccinated mice. a–d The levels of cytokines IFNγ (a), IL2 (b), IL4 (c), and IL10 (d) in sera of mice vaccinated with a DNA vaccine and its components were examined every 2 weeks after vaccination. The PBS group is used as a control. e The amount distribution of T lymphocyte subsets is determined in the peripheral blood of mice. The relative level of CD4/CD8 among DNA vaccine and its components in vaccinated mice. The statistical analysis is performed by two-way ANOVA post-Sidak's multiple comparison test (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001; ns: no statistical significance)

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Virology Journal

ISSN: 1743-422X