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Fig. 6 | Virology Journal

Fig. 6

From: Intranasal delivery of plasmids expressing bovine herpesvirus 1 gB/gC/gD proteins by polyethyleneimine magnetic beads activates long-term immune responses in mice

Fig. 6

Evaluation of humoral immune responses induced by DNA vaccine in vaccinated mice. a Total anti-BoHV1 antibody level in the indicated groups is examined from 1 to 17 weeks after the second vaccination (n = 3 mice per group at each time point). b Neutralizing titers of antisera from DNA vaccine vaccinated mice (n = 3 mice per group). The statistical analysis is performed by unpaired Student's t-test (***p < 0.001). c IgA level is detected in crushed lung liquid (n = 3 mice per group at each time point). The statistical analysis is performed by two-way ANOVA post Sidak’s multiple comparison test (###P < 0.001; ****,####,$$$$P < 0.0001)

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