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Fig. 4 | Virology Journal

Fig. 4

From: Intranasal delivery of plasmids expressing bovine herpesvirus 1 gB/gC/gD proteins by polyethyleneimine magnetic beads activates long-term immune responses in mice

Fig. 4

Changes of biochemical indicators in mouse sera after vaccination with DNA vaccine. a–e The concentration or activity unit of PHOS (a), UREA (b), ALKPU (c), AST (d), and CK (e) in serum is examined from 1 to 5 weeks after the second vaccination with PEI + DNA and PEI + DNA + PEG (n = 3 mice per group at each time point). The PBS group is used as a control. The symbol “#” indicates a comparison between PBS and PEI + DNA + PEG groups, "*" indicates a comparison between PBS and PEI + DNA groups. The statistical analysis is performed by two-way ANOVA post Sidak’s multiple comparison test (#P < 0.05; ##,**P < 0.01; ###,***P < 0.001; ####,****P < 0.0001)

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Virology Journal

ISSN: 1743-422X