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Table 1 Summary of therapies against SARS-CoV-2 targets. Listed are the main viral targets discussed with each drug class

From: Precision therapeutic targets for COVID-19

Viral target Drug classes Reference table
Spike protein/ACE2 binding Vaccines,
Neutralizing antibodies,
ARB and ACE inhibitors,
ACE-2 agonist,
Fibrosis inhibitor,
Hydroxylchloroquine/chloroquine
Additional file 1: Table 1
Main protease (MPro) HIV protease inhibitors,
HCV protease inhibitors,
Structural MPro inhibitors
Additional file 1: Table 2
RNA-dependent RNA polymerase (RdRp) Nucleoside analogs,
Influenza enzyme inhibitors,
Zinc supplementation
Additional file 1: Table 3
Whole virus Inactivated whole virus vaccine, convalescent plasma Additional file 1: Table 4