Table 1 Summary of therapies against SARS-CoV-2 targets. Listed are the main viral targets discussed with each drug class

Spike protein/ACE2 binding

Vaccines,

Neutralizing antibodies,

ARB and ACE inhibitors,

ACE-2 agonist,

Fibrosis inhibitor,

Hydroxylchloroquine/chloroquine

Additional file 1: Table 1

Main protease (M^Pro)

HIV protease inhibitors,

HCV protease inhibitors,

Structural M^Pro inhibitors

Additional file 1: Table 2

RNA-dependent RNA polymerase (RdRp)

Nucleoside analogs,

Influenza enzyme inhibitors,

Zinc supplementation

Additional file 1: Table 3

Whole virus

Inactivated whole virus vaccine, convalescent plasma

Additional file 1: Table 4