Table 1 Summary of therapies against SARS-CoV-2 targets. Listed are the main viral targets discussed with each drug class
| Viral target | Drug classes | Reference table |
|---|---|---|
| Spike protein/ACE2 binding |
Vaccines, Neutralizing antibodies, ARB and ACE inhibitors, ACE-2 agonist, Fibrosis inhibitor, Hydroxylchloroquine/chloroquine | Additional file 1: Table 1 |
| Main protease (MPro) |
HIV protease inhibitors, HCV protease inhibitors, Structural MPro inhibitors | Additional file 1: Table 2 |
| RNA-dependent RNA polymerase (RdRp) |
Nucleoside analogs, Influenza enzyme inhibitors, Zinc supplementation | Additional file 1: Table 3 |
| Whole virus | Inactivated whole virus vaccine, convalescent plasma | Additional file 1: Table 4 |