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Fig. 2 | Virology Journal

Fig. 2

From: When MARCH family proteins meet viral infections

Fig. 2

The proviral functions of MARCH family proteins. a HCV infection upregulates MARCH8 expression, and MARCH8 ubiquitinates the HCV NSP2 to promote the viral envelopment. b KSHV RTA promotes MARCH8 expression, and MARCH8 targets HLA-DRĪ± for degradation and finally promotes viral replication. HCV NSP2: hepatitis C virus nonstructural protein 2

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