Table 3 Secular trends in infection rates of different HPV subtypes from 2014 to 2019
HPV subtype | 2014, n (%) | 2015, n (%) | 2016, n (%) | 2017, n (%) | 2018, n (%) | 2019, n (%) | p Value for trend |
|---|---|---|---|---|---|---|---|
HPV16 | 28 (2.54) | 105 (2.59) | 106 (2.06) | 161 (2.53) | 154 (2.19) | 1 (3.23) | 0.0179 |
HPV18 | 13 (1.18) | 40 (0.99) | 27 (0.53) | 59 (0.93) | 66 (0.94) | 0 (0) | 0.0229 |
HPV31 | 9 (0.82) | 38 (0.94) | 39 (0.76) | 47 (0.74) | 38 (0.54) | 0 (0) | 0.0147 |
HPV33 | 23 (2.08) | 45 (1.11) | 62 (1.21) | 67 (1.05) | 58 (0.82) | 0 (0) | 0.0105 |
HPV35 | 10 (0.91) | 9 (0.22) | 11 (0.21) | 21 (0.33) | 18 (0.26) | 0 (0) | 0.0125 |
HPV39 | 16 (1.45) | 67 (1.65) | 77 (1.5) | 94 (1.48) | 100 (1.42) | 0 (0) | 0.0177 |
HPV45 | 7 (0.63) | 4 (0.1) | 8 (0.16) | 21 (0.33) | 13 (0.18) | 0 (0) | 0.0323 |
HPV51 | 15 (1.36) | 64 (1.58) | 67 (1.3) | 112 (1.76) | 97 (1.38) | 0 (0) | 0.0219 |
HPV52 | 39 (3.53) | 141 (3.48) | 128 (2.49) | 209 (3.29) | 238 (3.38) | 1 (3.23) | 0.0207 |
HPV53 | 23 (2.08) | 73 (1.8) | 70 (1.36) | 91(1.43) | 116 (1.65) | 0 (0) | 0.0167 |
HPV56 | 5 (0.45) | 19 (0.47) | 11 (0.21) | 49 (0.77) | 37 (0.53) | 0 (0) | 0.0496 |
HPV58 | 27 (2.45) | 100 (2.47) | 132 (2.57) | 155 (2.44) | 172 (2.44) | 0 (0) | 0.0189 |
HPV59 | 4 (0.36) | 12 (0.3) | 13 (0.25) | 24 (0.38) | 17 (0.24) | 0 (0) | 0.0217 |
HPV66 | 8 (0.72) | 28 (0.69) | 37 (0.72) | 54 (0.85) | 68 (0.97) | 0 (0) | 0.0286 |
HPV68 | 7 (0.63) | 32 (0.79) | 36 (0.7) | 53 (0.83) | 64 (0.91) | 0 (0) | 0.0259 |
HPV6 | 4 (0.36) | 23 (0.57) | 35 (0.68) | 35 (0.55) | 50 (0.71) | 0 (0) | 0.0273 |
HPV11 | 4 (0.36) | 25 (0.62) | 16 (0.31) | 43 (0.68) | 38 (0.54) | 0 (0) | 0.0327 |
HPV42 | 3 (0.27) | 1 (0.02) | 3 (0.06) | 27 (0.42) | 20 (0.28) | 0 (0) | 0.1135 |
HPV43 | 1 (0.09) | 1 (0.02) | 5 (0.1) | 11 (0.17) | 8 (0.11) | 0 (0) | 0.0631 |
HPV44 | 8 (0.72) | 8 (0.2) | 16 (0.31) | 31 (0.49) | 32 (0.45) | 0 (0) | 0.0319 |
HPV81 | 24 (2.17) | 89 (2.2) | 92 (1.79) | 102 (1.6) | 71 (1.01) | 1 (3.23) | 0.0132 |
Total | 278 | 924 | 991 | 1466 | 1475 | 3 |