Characteristics of human papillomavirus infection among women with cervical cytological abnormalities in the Zhoupu District, Shanghai City, China, 2014–2019

Table 3 Secular trends in infection rates of different HPV subtypes from 2014 to 2019

HPV subtype	2014, n (%)	2015, n (%)	2016, n (%)	2017, n (%)	2018, n (%)	2019, n (%)	p Value for trend
HPV16	28 (2.54)	105 (2.59)	106 (2.06)	161 (2.53)	154 (2.19)	1 (3.23)	0.0179
HPV18	13 (1.18)	40 (0.99)	27 (0.53)	59 (0.93)	66 (0.94)	0 (0)	0.0229
HPV31	9 (0.82)	38 (0.94)	39 (0.76)	47 (0.74)	38 (0.54)	0 (0)	0.0147
HPV33	23 (2.08)	45 (1.11)	62 (1.21)	67 (1.05)	58 (0.82)	0 (0)	0.0105
HPV35	10 (0.91)	9 (0.22)	11 (0.21)	21 (0.33)	18 (0.26)	0 (0)	0.0125
HPV39	16 (1.45)	67 (1.65)	77 (1.5)	94 (1.48)	100 (1.42)	0 (0)	0.0177
HPV45	7 (0.63)	4 (0.1)	8 (0.16)	21 (0.33)	13 (0.18)	0 (0)	0.0323
HPV51	15 (1.36)	64 (1.58)	67 (1.3)	112 (1.76)	97 (1.38)	0 (0)	0.0219
HPV52	39 (3.53)	141 (3.48)	128 (2.49)	209 (3.29)	238 (3.38)	1 (3.23)	0.0207
HPV53	23 (2.08)	73 (1.8)	70 (1.36)	91(1.43)	116 (1.65)	0 (0)	0.0167
HPV56	5 (0.45)	19 (0.47)	11 (0.21)	49 (0.77)	37 (0.53)	0 (0)	0.0496
HPV58	27 (2.45)	100 (2.47)	132 (2.57)	155 (2.44)	172 (2.44)	0 (0)	0.0189
HPV59	4 (0.36)	12 (0.3)	13 (0.25)	24 (0.38)	17 (0.24)	0 (0)	0.0217
HPV66	8 (0.72)	28 (0.69)	37 (0.72)	54 (0.85)	68 (0.97)	0 (0)	0.0286
HPV68	7 (0.63)	32 (0.79)	36 (0.7)	53 (0.83)	64 (0.91)	0 (0)	0.0259
HPV6	4 (0.36)	23 (0.57)	35 (0.68)	35 (0.55)	50 (0.71)	0 (0)	0.0273
HPV11	4 (0.36)	25 (0.62)	16 (0.31)	43 (0.68)	38 (0.54)	0 (0)	0.0327
HPV42	3 (0.27)	1 (0.02)	3 (0.06)	27 (0.42)	20 (0.28)	0 (0)	0.1135
HPV43	1 (0.09)	1 (0.02)	5 (0.1)	11 (0.17)	8 (0.11)	0 (0)	0.0631
HPV44	8 (0.72)	8 (0.2)	16 (0.31)	31 (0.49)	32 (0.45)	0 (0)	0.0319
HPV81	24 (2.17)	89 (2.2)	92 (1.79)	102 (1.6)	71 (1.01)	1 (3.23)	0.0132
Total	278	924	991	1466	1475	3

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