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Fig. 1 | Virology Journal

Fig. 1

From: Inhibitors of endosomal acidification suppress SARS-CoV-2 replication and relieve viral pneumonia in hACE2 transgenic mice

Fig. 1

Inhibitors of endosomal acidification improved the viability of Vero E6 cells after SARS-CoV-2 infection. a Viability of Vero E6 cells infected with different doses of SARS-CoV-2 for 48 h. b Cell viability after SARS-CoV-2 infection (0.008 MOI) at different time points. c Images of Vero E6 cells challenged with 0.008 MOI of SARS-CoV-2 for 48 h. d, e Cell viability of Vero E6 cells treated with chloroquine or bafilomycin after SARS-CoV-2 infection (0.008 MOI) for 48 h. f Colony formation assays of Vero E6 cells treated with chloroquine (40 μM) or bafilomycin A1 (100 nM) after SARS-CoV-2 infection (0.008 MOI) for 48 h. Three experiments were performed (n = 6 each group). *p < 0.05, **p < 0.01

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Virology Journal

ISSN: 1743-422X