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Fig. 6 | Virology Journal

Fig. 6

From: Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers

Fig. 6

HPgV-1 infection is associated with increased systemic levels of IL-2 and IL-17A. Cytokine, chemokine and growth factors levels were analysed by Luminex and levels compared between HPgV-1 negative (5′ UTR-, grey, n = 35) and HPgV-1 positive (5′ UTR + , purple, n = 9) volunteers. Absolute serum concentrations levels (pg/ml) of Interluekin-2 (IL-2) and Interluekin-17A (IL-17A) at samples taken before vaccination are shown. Significantly higher IL-2 and IL-17A are seen in the HPgV-1+ compared to the HPgV-1. Wilcoxon rank sum test was used to determine significance (P value * < 0.05) which are indicated on top of top for each group comparison

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