Role of antenatal plasma cytomegalovirus DNA levels on pregnancy outcome and HIV-1 vertical transmission among mothers in the University of Zimbabwe birth cohort study (UZBCS)

Table 4 Predictors for pre-term birth (< 37 weeks of pregnancy)

	Dependent variable: preterm birth (< 37 weeks)
	Without variable elimination	With variable elimination
Logistic regression results—odds ratios for preterm birth risk in HIV-infected women
Maternal CMV-DNA of > 50 copies/mL (yes/no)	2.71 (CI 0.94–7.88) *	2.37 (CI 0.88–6.29) *
Maternal HIV-RNA load (per 1000 copies/mL)	0.97 (CI 0.88–1.05)
Years with HIV diagnosis	0.73 (CI 0.54–0.92) **	0.73 (CI 0.55–0.91) **
On cART (yes/no)	0.53 (CI 0.18–1.52)
Maternal age (years)	1.06 (CI 0.98–1.15)

Logistic regression showing the association of different variables with preterm birth in HIV-infected but non-transmitting mothers. Results are presented as odds ratios; p-values are indicated as follows: *p < 0.1, **p < 0.05, ***p < 0.01. 121 participants were analysed (excluded: 2 due to missing data, 4 stillbirths and 11 MTCT cases)
CI: 95% confidence interval, CMV: cytomegalovirus, cART: combination anti-retroviral treatment, HIV: human immunodeficiency virus

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