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Table 3 Univariate and multivariate analysis of CKD

From: Cross-sectional retrospective analysis of clinical characteristics of chronic hepatitis B patients with oral antiviral treatment in eastern China

Variables Univariate analysis Multivariate analysis
P value B OR (95% CI) P
Age groups  < 0.001* 0.870 2.387 (2.118–2.691)  < 0.001*
Gender 0.322
HBsAg > 250 IU–mL  < 0.001*
HBeAg positive  < 0.001*
HBV DNA undetectable 0.407
ALT normalization 0.062
Diabetes mellitus  < 0.001* 0.396 1.486 (1.052–2.099) 0.025*
Hypertension  < 0.001* 0.939 2.557(1.915–3.412)  < 0.001*
Hepatic cirrhosis  < 0.001* 0.259 1.295(1.070–1.567) 0.008*
WBC (109/L) 0.439
PLT (109/L)  < 0.001*
Treatment duration 0.304
ADV-experienced  < 0.001* 0.497 1.644(1.321–2.046)  < 0.001*
TDF-experienced 0.542
  1. OR odds ratio, HBsAg hepatitis B virus surface antigen, HBeAg hepatitis B e antigen, HBV hepatitis B virus, ALT alanine transaminase, WBC white blood cell, PLT platelet, ADV adefovir dipivoxil, TDF tenofovir diester fumarate
  2. *Statistical significance