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Table 3 Univariate and multivariate analysis of CKD

From: Cross-sectional retrospective analysis of clinical characteristics of chronic hepatitis B patients with oral antiviral treatment in eastern China

Variables

Univariate analysis

Multivariate analysis

P value

B

OR (95% CI)

P

Age groups

 < 0.001*

0.870

2.387 (2.118–2.691)

 < 0.001*

Gender

0.322

–

–

–

HBsAg > 250 IU–mL

 < 0.001*

–

–

–

HBeAg positive

 < 0.001*

–

–

–

HBV DNA undetectable

0.407

–

–

–

ALT normalization

0.062

–

–

–

Diabetes mellitus

 < 0.001*

0.396

1.486 (1.052–2.099)

0.025*

Hypertension

 < 0.001*

0.939

2.557(1.915–3.412)

 < 0.001*

Hepatic cirrhosis

 < 0.001*

0.259

1.295(1.070–1.567)

0.008*

WBC (109/L)

0.439

–

–

–

PLT (109/L)

 < 0.001*

–

–

–

Treatment duration

0.304

–

–

–

ADV-experienced

 < 0.001*

0.497

1.644(1.321–2.046)

 < 0.001*

TDF-experienced

0.542

–

–

–

  1. OR odds ratio, HBsAg hepatitis B virus surface antigen, HBeAg hepatitis B e antigen, HBV hepatitis B virus, ALT alanine transaminase, WBC white blood cell, PLT platelet, ADV adefovir dipivoxil, TDF tenofovir diester fumarate
  2. *Statistical significance