TY - JOUR AU - Nobach, Daniel AU - Herden, Christiane PY - 2020 DA - 2020/01/30 TI - No evidence for European bats serving as reservoir for Borna disease virus 1 or other known mammalian orthobornaviruses JO - Virology Journal SP - 11 VL - 17 IS - 1 AB - The majority of emerging infectious diseases are zoonotic in nature and originate from wildlife reservoirs. Borna disease, caused by Borna disease virus 1 (BoDV-1), is an infectious disease affecting mammals, but recently it has also been shown to cause fatal encephalitis in humans. The endemic character of Borna disease points towards a nature-bound reservoir, with only one shrew species identified as reservoir host to date. Bats have been identified as reservoirs of a variety of zoonotic infectious agents. Endogenous borna-like elements in the genome of certain bat species additionally point towards co-evolution of bats with bornaviruses and therefore raise the question whether bats could serve as a potential reservoir of orthobornaviruses. SN - 1743-422X UR - https://doi.org/10.1186/s12985-020-1289-3 DO - 10.1186/s12985-020-1289-3 ID - Nobach2020 ER -