Fig. 3
From: Identification of cellular microRNA miR-188-3p with broad-spectrum anti-influenza A virus activity
Four miRNAs may bind to the potential target sites. a Circular map of the pGL3-cm vector. The potential target sites of these 5 miRNAs were inserted into the Bgl II and Kpn I sites. pRL-TK vector was cotransfected to keep the balance of each group. b The relative luciferase activity from pGL3-cm reporter vector and pRL-TK vector. The relative luciferase activity of negative control miRNA transfected group was normalized to 1. The miRNAs which downregulated luciferase expressions by 30% or more, compared to the negative control group, were selected for further research. * (P < 0.05), **(P < 0.01), ***(P < 0.001), results were significantly different from negative control miRNA group