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Table 1 Cytotoxicity and effective concentrations of integrase inhibitors in the TZM-bl cell system

From: Study on suitable analysis method for HIV-1 non-catalytic integrase inhibitor

  CC50 (nM) EC50 (nM) SI value
BI 224436 > 50,000.00 566.40 > 88.28
EVG 26,041.67 < 0.15 > 173,611.13
RAL > 50,000.00 10.38 > 4816.96
DTG > 50,000.00 1.60 > 31,250.00
  1. CC50, Half maximal cell cytotoxicity concentration; EC50, Half maximal effective concentration, SI value, Selectivity index, CC50/EC50
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