Table 1 Univariate analysis of factors associated with HR-HPV load
From: Analysis of influencing factors of viral load in patients with high-risk human papillomavirus
Variables | Parameters | Number of patients (%) | Simple endocervical sampling | Combination of endo-and ectocervical sampling | ||||
|---|---|---|---|---|---|---|---|---|
Mean (SD) of log10 transformed viral load | rs-valuea | P-value | Mean (SD) of log10 transformed viral load | rs-valuea | P-value | |||
Age (years) | 20–29 | 52 (19.0) | 0.57 (± 0.62) | 0.417 | 0.001 | 0.76 (± 0.61) | 0.349 | 0.001 |
30–39 | 91 (33.3) | 0.92 (± 0.73) | 1.11 (± 0.67) | |||||
40–49 | 99 (36.3) | 1.16 (± 0.78) | 1.29 (± 0.78) | |||||
50–59 | 25 (9.2) | 1.41 (± 0.69) | 1.63 (± 0.72) | |||||
60–69 | 6 (2.2) | 2.52 (± 0.13) | 2.56 (± 0.17) | |||||
Lesion severity | Negative | 90 (33.0) | 0.79 (± 0.39) | 0.371 | 0.002 | 0.88 (± 0.35) | 0.424 | < 0.001 |
LSIL | 93 (34.1) | 0.87 (± 0.91) | 1.03 (± 0.89) | |||||
HSIL/CC | 90 (33.0) | 1.41 (± 0.81) | 1.66 (± 0.70) | |||||
Multiple HPV types | No | 200 (73.3) | 0.92 (± 0.71) | 0.198 | 0.060 | 1.08 (± 0.65) | 0.237 | 0.024 |
Yes | 73 (26.7) | 1.29 (± 0.93) | 1.48 (± 0.95) | |||||
Area of lesions (cm2) | 0.0–0.49 | 174 (63.7) | 0.95 (± 0.74) | 0.292 | 0.017 | 1.04 (± 0.70) | 0.364 | < 0.001 |
0.5–0.99 | 46 (16.8) | 1.03 (± 0.72) | 1.22 (± 0.69) | |||||
1.0–1.49 | 24 (8.8) | 0.93 (± 0.82) | 1.41 (± 0.75) | |||||
1.5–1.99 | 6 (2.2) | 1.64 (± 0.94) | 1.80 (± 0.77) | |||||
2.0–2.49 | 10 (3.7) | 1.76 (± 0.86) | 1.90 (± 0.73) | |||||
2.5–2.99 | 7 (2.6) | 0.27 (± 0.14) | 0.72 (± 0.01) | |||||
3.0–3.49 | 6 (2.2) | 2.43 (± 0.41) | 2.89 (± 0.06) | |||||
Location of lesions (cm) | ≤ 0.5 | 125 (68.3) | 1.05 (± 0.72) | − 0.017 | 0.891 | 1.21 (± 0.65) | − 0.129 | 0.222 |
> 0.5 | 58 (31.7) | 0.90 (± 1.01) | 1.10 (± 1.09) | |||||