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Table 2 Mean KD values through One site-Specific binding analysis for interactions between HA antigen protein and a serial dilution of either 3′SL- or 6′SL-labeled receptors in each HA expression protein

From: Identifying novel amino acid substitutions of hemagglutinin involved in virulence enhancement in H7N9 virus strains

HAs KD FOR 3′SL (μM) KD FOR 6′SL (μM)
Anhui/1 & Shanghai/2 HA7 0.635 ± 0.188 0.753 ± 0.197
HA7 A135T 5.553 ± 1.232 0.147 ± 0.031
HA7 T71I 3.627 ± 0.518 0.388 ± 0.102
HA7 T157I 3.176 ± 0.921 0.231 ± 0.051
HA7 T71I-V223I 2.189 ± 0.518 0.127 ± 0.028
HA7 T71I-T157I-V223I 2.189 ± 0.204 0.268 ± 0.081
HA7 T71I-T157I-V223I-T40I 3.317 ± 0.300 0.231 ± 0.051