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Fig. 5 | Virology Journal

Fig. 5

From: Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus

Fig. 5

Prophylactic and therapeutic efficacy of 3C12 in mice. a Survival curves (left) and body weight loss (right) of BALB/c mice (five mice per experimental group) that received different concentrations 1 mg/kg, 5 mg/kg, 10 mg/kg, 20 mg/kg of 3C12 or PBS as a control intravenously (i.v.) 3 h before intranasal infection with 10-fold doses lethal to 50% of mice (MLD50) of AH/BRI99/16 virus. b Survival curves (left) and body weight loss (right) of mice (five per experimental condition) that received 15 mg/kg of 3C12 i.v. on day 0 (3 h before infection) or on day 1, 2, 3, 4, 5 post infection with 10 MLD50 AH/BRI99/16 virus. PBS as a control

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