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Fig. 4 | Virology Journal

Fig. 4

From: Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus

Fig. 4

Amino acid difference of the epitope of all the viruses used in the study. a The minimal epitope and its nearby amino acids were shown, with the minimal epitope in bold and mutations in colored. The reactivities of WB and IFA were shown on the right panel. “+” stood for reactivity, “-” stood for non-reactivity. ND stood for not done. b The location of the epitope recognized by 3C12 in the H1, H3, H5 and H9 HA protein 3D structures was generated by PyMOL. H1, H3, H5 and H9 were shown in red, yellow, blue and orange respectively. H1 PDB number: 2WRH; H3 PDB number: 2HMG; H5 PDB number: 2IBX

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