Table 2 Non-synonymous differences in the amino acid sequences in the coding regions between Kgs-c1 and other MDV strains

MDV004

23 kDa nuclear protein

76

S

R

S

S

R

R

S

S

R

R

R

R

R

MDV005

R-LORF7 (Meq)

77

E

K

K

K

K

E

E

E

E

E

E

K

E

80

Y

D

D

D

D

D

Y

Y

D

Y

Y

D

D

115

A

V

V

V

V

V

A

A

A

V

V

V

V

176/235*

S

P

A

P

P

P

R

R

P

P

P

P

P

217/ 276*

A

P

A

A

P

P

A

A

P

P

P

P

P

MDV006.6

B68 (VZV transducing protein)

14

I

T

T

T

T

T

T

T

T

T

T

T

T

MDV010

v-lipase

352

A

V

V

V

V

V

V

V

V

A

V

V

V

MDV015

UL3 (nuclear phosphoprotein)

6

C

G

G

G

G

G

G

G

G

G

G

P

G

MDV016

UL4 (nuclear protein)

244

I

V

V

V

V

V

V

V

V

V

V

V

V

MDV018

UL6 (DNA packaging, minor capsid protein)

243

D

N

N

N

A

N

N

N

N

N

N

N

N

MDV019

UL7 (DNA packaging/cleavage, capsid protein)

172

K

Q

Q

Q

Q

Q

Q

Q

Q

Q

Q

Q

Q

MDV020

UL8 (DNAhelicase-primase associated protein)

84

D

E

D

D

D

D

D

D

D

D

D

D

D

MDV020.5

UL8.5 (origin binding protein)

42

R

G

G

G

G

G

R

R

G

G

R

G

G

462

A

V

V

V

V

V

V

V

V

V

V

V

V

MDV021

UL9 (origin binding protein)

395

R

G

G

G

G

G

R

R

G

G

R

G

G

815

A

V

V

V

V

V

V

V

V

V

V

V

V

MDV040

UL27 (glycoprotein B)

537

F

S

S

S

S

S

S

S

S

S

S

S

S

MDV042

UL29 (single-strand DNA binding protein)

918

A

V

V

V

A

A

A

A

A

A

A

V

A

1,183

A

V

V

V

A

A

A

A

A

A

A

V

A

MDV043

UL30 (DNA polymerase)

1,087

D

N

N

N

N

N

N

N

D

N

N

N

N

1,095

A

V

V

V

V

V

V

V

A

V

V

V

V

MDV044

UL31 (nuclear phosphoprotein)

39

R

G

G

G

G

G

R

R

R

G

R

G

G

MDV046

UL32 (DNA packaging)

415

T

I

I

I

I

I

T

T

T

T

T

I

I

MDV047

UL34 (membrane phosphoprotein)

228

A

G

G

G

G

G

G

G

G

G

G

L

G

MDV049**

UL36 (large tegument protein)

3,241

E

K

E

E

E

E

E

E

E

E

E

E

E

MDV050

UL37 (tegument protein)

3

A

V

V

A

A

A

A

A

A

A

A

V

A

258

R

Q

Q

Q

Q

Q

R

R

R

R

R

Q

Q

521

H

R

R

R

R

R

H

H

H

H

H

R

R

MDV051

UL38 (capsid protein)

68

A

T

T

T

T

T

A

A

A

A

A

T

A

MDV055

UL42 (DNA polymerase)

114

I

V

V

V

V

V

I

I

I

I

I

V

V

166

V

A

A

A

A

A

A

A

A

V

A

A

A

MDV056

UL43 (probable membrane protein)

305

E

K

K

K

E

K

E

E

E

T

E

K

E

399

I

V

I

V

V

V

V

V

V

V

V

V

V

MDV071

LORF10 (VZV ORF2)

34

L

W

W

W

L

L

L

L

L

W

L

W

L

MDV073

R-LORF14a (pp38)

109

G

E

E

E

E

G

G

G

G

G

G

G

G

115

L

P

P

P

P

P

P

P

P

P

P

P

P

MDV084

ICP4

181

S

P

S

P

P

P

P

P

P

P

P

P

P

532

R

C

C

C

R

C

R

R

R

R

R

C

C

1,084

L

P

P

P

L

L

L

L

L

L

S

P

L

1,993

P

L

L

L

L

L

P

P

P

P

P

L

L

2,017

E

K

K

K

K

K

E

E

E

E

E

K

K

2,111

R

L

L

L

R

P

R

R

R

R

R

L

L

MDV091

US2 (transmission associated protein)

51

A

V

V

V

A

V

A

V

A

A

A

V

A

MDV092

US3 (serine/threonine protein kinase)

4

T

S

S

S

T

S

T

S

T

S

T

S

T

109

P

S

S

S

P

P

P

P

P

P

P

S

P

MDV095

US7 (glycoprotein I)

3

V

L

L

L

V

L

V

L

V

L

Y

L

L

112

G

H

H

H

G

H

G

H

G

D

G

D

H

142

S

A

A

A

S

A

S

A

S

A

S

A

A

155

V

A

A

A

V

A

V

A

V

A

V

A

A

223

V

I

I

I

V

I

V

I

V

I

V

I

I

MDV096

US8 (glycoprotein E)

67

I

V

V

V

V

V

V

V

V

V

V

V

V

370

I

V

V

V

V

V

V

V

I

I

V

V

V

392

L

I

I

I

I

I

L

I

L

L

L

I

I

455

A

D

D

D

D

D

A

D

A

A

A

T

D

469

D

A

A

A

A

A

D

A

D

D

D

A

A