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Fig. 7 | Virology Journal

Fig. 7

From: The recombinant pseudorabies virus expressing African swine fever virus CD2v protein is safe and effective in mice

Fig. 7

PRV-Fa, PRV-ΔgE/ΔgI/ΔTK and PRV-ΔgE/ΔgI/ΔTK-(CD2v) inoculation led to T cells' activation. ad The result of CD3+CD69+ T cell flow analysis. fi: The result of CD4+CD69+ T cell flow analysis. kn: The result of CD8+CD69+ T cell flow analysis. The data showed the changes of the percentage of CD3+CD69+ (e), CD4+CD69+ (j), CD8+CD69+ (o) T cells in total PBMCs. Five-week-old SPF-ICR mice were inoculated with 1 × 105 TCID50 viruses by intramuscular injection in the right hind leg. The control group was injected with 100 μL DMEM. When the PRV-Fa-infected group started to scratch (about 72 hpi), the target cells were collected and analyzed by flow cytometry. Unpaired t-test was performed by GraphPad Prism 5.0, GraphPad Software (San Diego, CA, USA), *p < 0.05, **p < 0.01, ***p < 0.001, (n = 5/each group)

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