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Table 1 Epidemiological, clinical, and virologic characteristics of the study sample

From: Italian observational study on HPV infection, E6, and p16 expression in men with penile cancer

Mean age (SD), years 68.0 (11.6)
Age ≥ 55 years, n (%) 28/32 (87.5)
Civil status, n (%)
Married 13/17 (76.5)
Single 2/17 (11.8)
Widower 2/17 (11.8)
Occupational status, n (%)
Employed 7 (38.9)
Retired 11 (61.1)
Familiarity for carcinoma, n (%) 1/15 (6.7)
Suspected diagnosis of carcinoma, n (%) 23/24 (92.0)
Cancer diagnosed before 2010, n (%) 10.32 (31.3)
Anatomic site, n (%)
Glans 24/32 (75.0)
Penis 8/32 (25.0)
Histopathological results, n (%)
Squamous Cell Carcinoma 30/32 (93.8)
Hyperplasia 1/32 (3.1)
Fibrosis 1/32 (3.1)
Well differentiated, n (%) 19/32 (59.4)
Moderately differentiated, n (%) 8/32 (25.0)
Poorly differentiated, n (%) 5/32 (15.6)
Histopathological grading (AJCC), n (%)
G1 19/32 (59.4)
G2 8/32 (25.0)
G3 5/32 (15.6)
Primary tumor (T) (AJCC), n (%)
Tis 3/32 (9.4)
T1 18/32 (56.3)
T1a 2/32 (6.3)
T1b 1/32 (3.1)
T2 1/32 (3.1)
T3 4/32 (12.5)
NC 3/32 (9.4)
HPV positivity, n (%) 9/32 (28.1)
HPV-16 7/32 (21.9)
HPV-56 2/32 (6.3)
HPV-35 1/32 (3.1)
p-16 immunohistochemistry positivity, n (%) 7/32 (21.9)
E6 gene positivity, n (%) 5/7 (71.4)
Outcome, died 14/32 (43.8)
  1. *Denominators of the collected variables can change based on the available information retrieved from the medical files