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Table 2 I. Distribution of HPV negative women, women with transient HPV16 infection and women with persistent HPV16 infection and CIN2+ in the four clusters. Proportion of total number of samples given in percent are reported within parenthesis. II. Statistical comparisons of the frequencies of non-Lactobacillus clusters (cluster 3 and 4) based on baseline samples of HPV16 negative women versus those with transient and persistent HPV16 infection, and for the follow up sample between women with transient HPV16 and persistent HPV16 infection

From: Temporal changes in the vaginal microbiota in self-samples and its association with persistent HPV16 infection and CIN2+

I. Distribution of samples per cluster

 

Cluster #1

Cluster #2

Cluster #3

Cluster #4

HPV negative

14 (43.8)

9 (28.1)

7 (21.9)

2 (6.3)

HPV16 transient, baseline sample

3 (11.5)

10 (38.5)

12 (46.2)

1 (3.8)

HPV16 persistent, baseline sample

13 (34.1)

11 (28.9)

11 (28.9)

3 (7.9)

HPV16 transient, follow up sample

4 (15.4)

11 (42.3)

10 (38.5)

1 (3.8)

HPV16 persistent, follow up sample

15 (39.5)

12 (31.6)

7 (18.4)

4 (10.5)

II. Statistical comparisons

 

p value

q value

  

a. Baseline sample

 HPV16 negative versus transient and persistent HPV16 infectiona

0.0173

0.0519

  

 Transient HPV16 versus persistent HPV16 infectiona

0.1433

0.4299

  

b. Follow up sample

 Transient HPV16 versus persistent HPV16 infectiona

0.423

1

  
  1. p value for binomial testing
  2. aTwo-sided binomial testing