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Fig. 4 | Virology Journal

Fig. 4

From: HLA-associated protection of lymphocytes during influenza virus infection

Fig. 4

Influenza Virus (IAV)-infected Neuraminidase-treated HLA-A2-homozygous Lymphocytes Serve as Infectious Foci for MDCK Cells. This representative image shows results using cells from HLA-A2-homozygous donor number 2. Lymphocytes were layered over MDCK cell monolayers which were overlaid subsequently with 0.6% agarose, incubated at 37 °C for 48 h, then fixed and stained with methylene blue to facilitate plaque quantification. Based on previous studies, one plaque was assumed to be caused by one infected cell

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