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Fig. 1 | Virology Journal

Fig. 1

From: Complete protection for mice conferred by a DNA vaccine based on the Japanese encephalitis virus P3 strain used to prepare the inactivated vaccine in China

Fig. 1

Mouse experimental workflow. Groups of mice were immunized by intramuscular electroporation with 50 μg of either the pV-JP3ME DNA vaccine or pV in each limb individually and were boosted twice at three-week intervals. Splenocytes were obtained 1 week after the final immunization, and sera were collected 3 weeks after the final immunization. Subsequently, the vaccinated mice were challenged with 1 × 105 PFU of the JEV P3 strain. The body weight changes and the survival rates were observed for 12 consecutive days after the challenge

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Virology Journal

ISSN: 1743-422X