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Table 5 Distribution of HPV infection with a single genotype and multiple genotypes in women (n = 3134)

From: Prevalence of human papillomavirus genotypes and precancerous cervical lesions in a screening population in Beijing, China: analysis of results from China’s top 3 hospital, 2009–2019

Types HSIL LSIL Normal Total
n % n % n % n %
Total 1745   1354   35   3134  
Total HPV (+) 1640 93.98% 1195 88.26% 20 57.14% 2803 89.44%
HPV6,11 36 2.20% 64 5.36% 4 20.00% 104 3.71%
HPV16 926 56.46% 289 24.18% 8 40.00% 1223 43.63%
HPV18 120 7.32% 132 11.05%    252 8.99%
HPV21 38 2.32% 14 1.17%    52 1.86%
HPV31 135 8.23% 56 4.69% 5 25.00% 196 6.99%
HPV33 123 7.50% 45 3.77% 1 5.00% 169 6.03%
HPV35 53 3.23% 57 4.77% 1 5.00% 111 3.96%
HPV39 70 4.27% 128 10.71%    198 7.06%
HPV45 36 2.20% 26 2.18% 2 10.00% 64 2.28%
HPV51 126 7.68% 156 13.05% 1 5.00% 283 10.10%
HPV52 266 16.22% 263 22.01% 3 15.00% 532 18.98%
HPV56 102 6.22% 170 14.23% 1 5.00% 273 9.74%
HPV58 302 18.41% 255 21.34% 3 15.00% 560 19.98%
HPV59 71 4.33% 68 5.69% 2 10.00% 141 5.03%
HPV66 40 2.44% 71 5.94% 3 15.00% 114 4.07%
HPV67 22 1.34% 7 0.59% 2 10.00%   
HPV68 34 2.07% 87 7.28% 1 5.00% 122 4.35%
HPV82 27 1.65% 22 1.84%    49 1.75%
  1. The proportion of HPV16 type in HSIL was significantly different from that of other high-risk type HPV, P < 0.05 (HPV58, χ2 = 30.97; HPV52, χ2 = 34.72; HPV31, χ2 = 52.94; HPV51, χ2 = 52.94)
  2. The proportion of HPV58 type in HSIL was significantly different from that of other high-risk type HPV, p < 0.05 (HPV16, χ2 = 30.97; HPV31, χ2 = 4.42; HPV51, χ2 = 4.42) except for HPV52, χ2 = 0.14, p = 0.71 > 0.05
  3. The proportion of HPV52 type in HSIL was significantly different from that of HPV16, χ2 = 34.72, p < 0.05 except for HPV58, χ2 = 0.14, p = 0.71 > 0.05; HPV31, χ2 = 3.03, p = 0.08 > 0.05; HPV51, χ2 = 3.03, p = 0.08 > 0.05
  4. The proportion of HPV16 type in LSIL was significantly different from that of HPV51, χ2 = 4.01, p = 0.045 < 0.05 except for HPV52, χ2 = 0.11, p = 0.72 > 0.05; HPV58, χ2 = 0.26, p = 0.611 > 0.05; HPV56, χ2 = 3.25, p = 0.071 > 0.05
  5. The proportion of HPV52 type in LSIL was not significantly different from that of following HPV type, P > 0.05 (HPV16, χ2 = 0.11, p = 0. 72; HPV58, χ2 = 0.03, p = 0.86; HPV56, χ2 = 2.17, p = 0.14; HPV51, χ2 = 2.91, p = 0.088
  6. The proportion of HPV58 type in LSIL was not significantly different from that of following HPV type, P > 0.05 (HPV58, χ2 = 0.26, p = 0.61; HPV52, χ2 = 0.03, p = 0.86; HPV56, χ2 = 1.70, p = 0.19; HPV51, χ2 = 2.27, p = 0.13
  7. The proportion of HPV16 type in normal cervical lesion was significantly different from that of following HPV type, P < 0.05 (HPV31, χ2 = 5.13, p = 0.024; HPV6,11,52,58,66, Fisher test, p < 0.0001;)
  8. The proportion of HPV31 type in normal cervical lesion was significantly different from HPV16, χ2 = 5.13, p = 0.024 < 0.05; except for HPV6,11,52,58,66 (Fisher test, p = 0.111 > 0.05
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