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Table 5 Analysis of amino acid sequences of PB2, PB1, PA, NP, M1, M2, M1, and NS2 of Algerians AIV H9N2 viruses in comparison with references strains

From: Full-length genome sequences of the first H9N2 avian influenza viruses isolated in the Northeast of Algeria

Genes Molecular determinants of virulence Molecular determinants of host specificity and host pathogenicity Molecular determinants of drug resistance Miscellaneous
Sites ALG HK-G1 Virulent Sites ALG HK-G1 Mammalian preference sites ALG HK-G1
PB2 89 V V L 44 A A S   
147 V M L 64 M M T
250 V V G 81 T T M
253 D D N 158 E E G
404 F F L 190 K R K
504 V V V 199 A A S
     271 T T A
     318 R K R
     339 K K T
     526 K K R
     543 E E D
     588 A A V
  590 S S  
591 Q Q K
627 E E K
643 S S T
655 V A V
661 T T A
666 T T I
701 D D N
702 Q K R
714 S S R
PB1 105 N N S 13 P P P   
317 M I I 207 K K R
577 K K E 336 V V I
622 G G G 375 N N S
     436 Y Y H
     578 K K Q
     677 T T M
PB1-F2       Truncated protein of 52 aa
PA 127 V V V 28 P P L   
550 L L L 44 V V I
672 L L L 55 D D N
     57 R R Q
     63 V V I
     97 T T I
     100 I V A
     133 E E G
     142 K K N/E
     225 S S C
     241 C C Y
     268 L L I
     312 R K R
     343 A A S
     347 D D E
     356 K K R
     382 E E D
     383 D D D
     400 T L L
     404 A A S
     409 N S N
     515 T T T
     552 T T S
     556 Q Q R
     573 I I V
     615 K R N
PA-X       Full length 252 aa
NP 210 D D D 31 R R K   
     33 V V I
     34 G G N
     61 I I L
     100 R R V
     109 I I V
     127 E E D
     136 M M M
     214 R R K
     283 L L P
     293 R R K
     305 R R K
     313 F F Y
     357 Q Q K
     372 D E D
     375 D D G/E
     398 Q Q Q
     422 R R K
     430 K K  
     442 T T A
     455 D D E
     480 D D  
M1 30 D D D 15 I I I   
43 M M M 115 V R I
215 A A A 121 T T A
     137 T T A
M2 64 S S S/A/F 11 T T I 26 L L  
69 P P P 16 D G G/D 27 V V
  28 V V I/V 31 N S
55 F F F 34 G G
57 Y Y H 38 L L
86 V V A    
NS1 42 S S S 227 G E K/R     Non 80TIASV84 deletion
GSEV PL motif
92 D E E        
103 L L F        
106 M I M        
149 A A A        
189 D D N        
NS2 31 M M I         
56 H H Y        
  1. ALG currents Algerians AIV H9N2, HK-G1 A/quail/Hong Kong/G1/97