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Table 2 Genotype, allele frequencies of SLC10A1 gene polymorphism in the study participants

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

SNP

Controls (n = 146)

Cases (n = 146)

P-value

n (%)

Allele frequency

n (%)

Allele frequency

C

T

C

T

rs2296651

 

0.969

0.031

 

0.884

0.116

< 0.0001

 CC

137 (93.8)

  

114 (78.1)

  

0.0001

 CT

9 (6.2)

  

27 (18.5)

  

0.001

 TT

0a

  

5 (3.4)

  

0.025

HWE-P

1.00

0.112

 

rs61745930

 

0.014

0.986

 

0.028

0.972

0.238

 TT

142 (97.3)

  

138 (94.5)

  

0.228

 CT

0

  

0

  

 CC

4 (2.7)

  

8 (5.5)

  

0.228

HWE-P

0.003

0.009

0.888

rs4646287

 

0.907

0.093

 

0.918

0.082

0.767

 CC

120 (82.2)

  

123 (84.2)

  

0.648

 CT

24 (16.4)

  

21 (14.4)

  

0.636

 TT

2 (1.4)

  

2 (1.4)

  

1.00

HWE-P

0.763

0.549

 
  1. Cases: HBV seropositive, Controls: HBV seronegative, HWE-P Hardy-Weinberg equation p-values, P-values represents the chi-square test to compare genotype frequency between case-and control -subjects. P-values for chi-squared test for variant allelic frequency based on HWE, p < 0.05 depicts it not consistent with HWE