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Table 2 Genotype, allele frequencies of SLC10A1 gene polymorphism in the study participants

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

SNP Controls (n = 146) Cases (n = 146) P-value
n (%) Allele frequency n (%) Allele frequency
C T C T
rs2296651   0.969 0.031   0.884 0.116 < 0.0001
 CC 137 (93.8)    114 (78.1)    0.0001
 CT 9 (6.2)    27 (18.5)    0.001
 TT 0a    5 (3.4)    0.025
HWE-P 1.00 0.112  
rs61745930   0.014 0.986   0.028 0.972 0.238
 TT 142 (97.3)    138 (94.5)    0.228
 CT 0    0   
 CC 4 (2.7)    8 (5.5)    0.228
HWE-P 0.003 0.009 0.888
rs4646287   0.907 0.093   0.918 0.082 0.767
 CC 120 (82.2)    123 (84.2)    0.648
 CT 24 (16.4)    21 (14.4)    0.636
 TT 2 (1.4)    2 (1.4)    1.00
HWE-P 0.763 0.549  
  1. Cases: HBV seropositive, Controls: HBV seronegative, HWE-P Hardy-Weinberg equation p-values, P-values represents the chi-square test to compare genotype frequency between case-and control -subjects. P-values for chi-squared test for variant allelic frequency based on HWE, p < 0.05 depicts it not consistent with HWE
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