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Table 1 Descriptive summary of demographic and liver function indices of the study participants

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

Variables Control
n = 146
Cases
n = 146
P-value
Gendera    0.193
 Male 68 (46.6) 57 (39.0)  
 Female 78 (53.4) 89 (61.0)  
Age (years) 31.3 ± 10.0 30.6 ± 8.1 0.542
Total Bilirubin (μmol/L) 12.73 ± 5.29 14.89 ± 6.56 0.002
Direct Bilirubin (μmol/L) 6.59 ± 3.54 6.44 ± 3.22 0.700
Indirect Bilirubin (μmol/L) 6.08 ± 3.27 8.13 ± 4.50 < 0.0001
Total protein (g/L) 72.35 ± 7.52 70.83 ± 9.97 0.141
Albumin (g/L) 41.69 ± 5.53 39.72 ± 7.35 0.010
ALT (U/L 26.42 ± 11.79 27.33 ± 13.59 0.540
AST (U/L) 27.14 ± 13.30 30.35 ± 19.10 0.007
GGT (U/L) 33.37 ± 16.99 27.72 ± 12.73 0.042
ALP (U/L) 159.7 ± 55.8 159.0 ± 53. 0.914
De Ritis ratio 1.0 (0.80–1.26) 1.03 (0.76–1.47) 0.631
APRI index 0.30 (0.20–0.43) 0.37 (0.25–0.50) 0.003
FIB-4 0.68 (0.49–1.05) 0.80 (0.60–1.18) 0.009
RPR 0.06 (0.04–0.07) 0.07 (0.06–0.10) < 0.0001
  1. Data is presented as means ± standard deviation. Variables with the superscript “a” were presented as frequency and subgroup proportions. ALT Alanine aminotransferase, AST Aspartate aminotransferase, GGT Gamma-glutamyl transferase, APRI index Aspartate aminotransferase-to-platelet ratio index, FIB-4 fibrosis index based on four factors, RPR RDW-to-platelet ratio, P < 0.05 is considered statistically significant