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Table 1 Descriptive summary of demographic and liver function indices of the study participants

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

Variables

Control

n = 146

Cases

n = 146

P-value

Gendera

  

0.193

 Male

68 (46.6)

57 (39.0)

 

 Female

78 (53.4)

89 (61.0)

 

Age (years)

31.3 ± 10.0

30.6 ± 8.1

0.542

Total Bilirubin (μmol/L)

12.73 ± 5.29

14.89 ± 6.56

0.002

Direct Bilirubin (μmol/L)

6.59 ± 3.54

6.44 ± 3.22

0.700

Indirect Bilirubin (μmol/L)

6.08 ± 3.27

8.13 ± 4.50

< 0.0001

Total protein (g/L)

72.35 ± 7.52

70.83 ± 9.97

0.141

Albumin (g/L)

41.69 ± 5.53

39.72 ± 7.35

0.010

ALT (U/L

26.42 ± 11.79

27.33 ± 13.59

0.540

AST (U/L)

27.14 ± 13.30

30.35 ± 19.10

0.007

GGT (U/L)

33.37 ± 16.99

27.72 ± 12.73

0.042

ALP (U/L)

159.7 ± 55.8

159.0 ± 53.

0.914

De Ritis ratio

1.0 (0.80–1.26)

1.03 (0.76–1.47)

0.631

APRI index

0.30 (0.20–0.43)

0.37 (0.25–0.50)

0.003

FIB-4

0.68 (0.49–1.05)

0.80 (0.60–1.18)

0.009

RPR

0.06 (0.04–0.07)

0.07 (0.06–0.10)

< 0.0001

  1. Data is presented as means ± standard deviation. Variables with the superscript “a” were presented as frequency and subgroup proportions. ALT Alanine aminotransferase, AST Aspartate aminotransferase, GGT Gamma-glutamyl transferase, APRI index Aspartate aminotransferase-to-platelet ratio index, FIB-4 fibrosis index based on four factors, RPR RDW-to-platelet ratio, P < 0.05 is considered statistically significant